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Procedures

What is PGT (genetic testing of embryos) and do I need it?

Medcasts editorial team

Pre-implantation genetic testing (PGT) tests embryos before transfer. Three types:

• PGT-A (aneuploidy): tests for chromosome number abnormalities. Used for advanced maternal age (≥38), recurrent miscarriage, prior IVF failure.

• PGT-M (monogenic): tests for specific genetic diseases when known parental mutations exist (cystic fibrosis, sickle cell, BRCA, etc.).

• PGT-SR (structural rearrangement): for parents with known chromosomal translocations.

You need PGT-A if: ≥38 years, ≥2 miscarriages, ≥2 failed IVF cycles, or known elevated chromosomal risk.

You don't typically need PGT-A if: <35 years, no miscarriage history, first cycle. Cost-benefit doesn't justify it for low-risk patients in many cases.

This answer is general information, not medical advice. Your own doctor should confirm what applies to your case.

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