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Condition · 2 treatment paths

Endometrial Cancer

Endometrial cancer is cancer of the lining of the womb. It most often affects women after the menopause and is usually found at an early stage.

Severe

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Treatment paths
2Treatment paths
Specialties
2Specialties
Typical severity
SevereTypical severity

About endometrial cancer

What to know

Postmenopausal bleeding is the key symptom, and irregular bleeding or discharge can occur in younger women. Investigation includes pelvic ultrasound, endometrial biopsy and sometimes hysteroscopy, with MRI or CT for staging. Because bleeding appears early, most cases are diagnosed while the cancer is confined to the womb, and outcomes are generally good.

The main treatment is hysterectomy with removal of both tubes and ovaries (bilateral salpingo-oophorectomy), often by keyhole or robotic surgery, sometimes with lymph node assessment. Radiotherapy, brachytherapy, chemotherapy or hormonal treatment are added depending on the stage, grade and molecular features. Treatment is widely available locally, so travel abroad is usually for second opinions or robotic surgery.

Pre-flight workup

Tests to have already done

  • Biopsy or curettage pathology report giving the histological type and grade, such as endometrioid or serous.
  • Pelvic MRI or ultrasound reports, and CT of the chest and abdomen if done for staging.
  • Molecular or immunohistochemistry results such as mismatch repair status and p53, which now guide treatment.
  • Blood tests, and for suspected family history of Lynch syndrome, relevant genetic information.
  • Your general health summary: weight, diabetes, heart disease and previous surgery, which affect the surgical approach.
  • A note of whether you wish to preserve fertility, if you are premenopausal.

Second opinion

When to get a second look

  • You are premenopausal and want to preserve fertility but have been told hysterectomy is the only option.
  • The tumour type is serous, clear cell or high grade and you want to confirm the plan for chemotherapy.
  • Final pathology after surgery suggests more advanced disease and extra treatment is recommended.
  • Molecular testing has not been done and you are unsure it would change the plan.

Talking to your doctor

Questions to ask

  1. What type, grade and stage is my cancer, and what do the molecular results show?
  2. Is a robotic or keyhole hysterectomy suitable, and will lymph nodes be assessed?
  3. Will I need radiotherapy or chemotherapy afterwards?
  4. Are there fertility-sparing options for my situation, and how safe are they?
  5. Should I or my relatives be tested for Lynch syndrome?
  6. What follow-up schedule and symptoms should I watch for?

Outlook

Realistic prognosis

Endometrial cancer is usually found early because of bleeding, and the outlook is generally good: for early-stage disease confined to the womb, five-year survival is high. Prognosis depends on stage, grade, tumour type and molecular features, and falls for serous or advanced disease. Surgery alone cures most early, low-grade cancers, while higher-risk cases benefit from radiotherapy or chemotherapy. Recurrence is mostly in the first few years.

Diagnostic workup

Before you pick a hospital, get the workup right

Severe — workup typically within 48–72 hours

Picking the right treatment is downstream of a complete diagnosis. Skip steps here and the destination surgeon usually re-orders them anyway — at higher cost and another week on the ground.

  1. Confirm the diagnosis on imaging or labs

    For endometrial cancer, plan on the workup your home doctor would order anyway — typically a recent specialist consult plus the imaging / labs the destination team will need to quote accurately. Anything older than 90 days usually gets re-done.

  2. See a oncology specialist locally first

    An in-person clinical exam at home — even a single consult — costs little and dramatically improves the destination plan. Bring back: written impression, recommended procedure, surgical-risk class, and any contra-indications.

  3. Send us the file for a free second opinion

    Two surgeons in our medical panel review the workup independently. They tell you whether they'd operate, watch, or refer — even if that means recommending against travel.

  4. Pick a path with timeline + cost in writing

    Once a treatment is the right call, we line up 2–3 hospital options with itemized quotes, surgeon profiles, and a travel timeline. You hold the file — switch hospitals or step away at any point.

04 · FAQ

Common questions about endometrial cancer

Is hysterectomy always needed?

Usually yes, as standard treatment. In selected younger women with early, low-grade cancer, hormone treatment may be tried to preserve fertility, with close monitoring.

Will I need chemotherapy or radiotherapy?

Many early cancers need only surgery. Extra treatment is advised when the final pathology shows higher-risk features such as deep invasion, high grade or lymph node spread.

Can it come back?

Recurrence is possible, mostly within the first few years, and is more likely with higher-grade or advanced disease. Follow-up visits aim to detect it early.

Clinical context

Working up endometrial cancer properly

A condition like endometrial cancer is rarely well-served by jumping straight to treatment shopping. The sequence below is what a oncology specialist would expect to see completed — and the absence of any step is the right cue to delay travel decisions.

Diagnostic workup, in sequence

  1. First-line clinical assessment

    History, physical exam, and risk-factor review by a senior generalist or oncology specialist. Symptoms list, family history, prior workup notes, and current medication list should travel with the patient.

  2. Standard imaging + labs

    Baseline blood work, condition-specific imaging (ultrasound / X-ray / MRI / CT — depending on indication), and ECG / pulmonary function as relevant. Bring digital copies of any prior imaging — saves repeat scans and the cost that goes with them.

  3. Specialist diagnostic workup

    Procedure-specific tests — biopsy, cardiac catheterisation, endoscopy, or genetic / molecular profiling depending on the suspected diagnosis. Done at the centre that will treat, ideally, so results integrate cleanly into the treatment plan.

  4. Multidisciplinary review (where indicated)

    Cancer, complex cardiac, transplant, and rare-disease cases should be reviewed by a multidisciplinary panel — surgical, medical, imaging, and pathology — before any treatment commits. Single-discipline plans for complex disease are a quality red flag.

When to escalate urgently

  • Acute worsening of established symptoms — sudden chest pain, shortness of breath at rest, neurological deficit, severe bleeding, persistent high fever.
  • Loss of consciousness, severe persistent vomiting, or any focal neurological event.
  • Symptoms in the early hours of onset that fit a time-sensitive treatment window (stroke, MI, sepsis) — every hour costs outcome.
  • If you are travelling internationally for treatment and develop these symptoms in transit, divert to the nearest emergency department; do not wait to reach the planned destination.

Before you book international travel

  • Confirm your specific diagnosis is fully worked up before you commit to a treatment plan abroad. Travelling for the workup is fine; travelling for treatment without the workup done is not.
  • Get your case reviewed remotely by the destination centre's team before you book flights — credible international patient programs review imaging + reports before they confirm the surgical plan.
  • Bring a digital + physical copy of your full medical record: imaging on USB drive in DICOM format, labs in PDF, current medication list with dosages, allergies, and any prior surgical reports.
  • Plan for longer recovery + post-discharge therapy continuation before you fly — the surgery itself is rarely the bottleneck.
  • Confirm that follow-up imaging and any necessary in-person reviews can be done at home — a treatment plan that requires repeat international trips is more burdensome (and more expensive) than the headline procedure.
How this page is made

Methodology and editorial standards

This endometrial cancer overview is written by the editorial team from published Oncology sources and lists 2 treatment options offered by hospitals on our network. The page shows its last-updated date. Clinical descriptions are editorial — your treating clinician confirms what's right for your specific case.

  1. Hospital data. Hospital details are compiled from public sources and hospital websites. Accreditation (JCI, NABH and others) is shown where we hold a record of it. Always ask the hospital for its current certificate.
  2. Doctor credentials. Qualifications, specialty and bio come from the doctor's hospital profile. Licence is checked against the national medical-council register only where the profile shows a "Licence verified" badge with a date.
  3. Prices. Price ranges are indicative, compiled from hospital price lists and packages and shown with the date last updated. The hospital's written quote is what you pay against.
  4. Clinical text. Written by the Medcasts editorial team from published clinical sources. Unless a named reviewer is shown on the page, it has not been reviewed by a doctor.
  5. Independence. Hospitals cannot pay to change their position on our pages.
Data sources for this page
Peer-reviewed clinical guidelines (NCCN, ESMO, ESC, AHA, NICE — by indication)WHO ICD-11 condition classificationNational medical society treatment protocolsJCI accreditation registry

Next step · Endometrial Cancer

Free second opinion on your Endometrial case.

Share imaging and the current plan. Multidisciplinary board returns a written opinion within 5–10 working days — no obligation to travel.